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Image Search Results
Journal: Molecular Medicine Reports
Article Title: In vivo treatment of rat arterial adventitia with interleukin-1β induces intimal proliferation via the JAK2/STAT3 signaling pathway
doi: 10.3892/mmr.2016.4982
Figure Lengend Snippet: Adventitial administration of interleukin-1β activated the JAK2/STAT3 pathway in the vascular tissue. (A) Protein expression levels of JAK2, STAT3, p-JAK2 and p-STAT3 in vascular tissue analyzed by western blot analysis. (B) Gray scale analysis of JAK2, STAT3, p-JAK2 and p-STAT3 protein expression levels. The results are expressed as the mean ± standard deviation (n=5). # P<0.05 vs. the control. Immunohistochemical staining was conducted to detect the expression of (C) p-JAK2 and (D) p-STAT3 in the vascular tissue derived from experimental group 8 h post-surgery (magnification, ×400). JAK, janus kinase; STAT, signal transducer and activator of transcription; p-, phosphorylated; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.
Article Snippet: Co., Ltd., Nanjing, China),
Techniques: Expressing, Western Blot, Standard Deviation, Immunohistochemical staining, Staining, Derivative Assay
Journal: Molecular Medicine Reports
Article Title: In vivo treatment of rat arterial adventitia with interleukin-1β induces intimal proliferation via the JAK2/STAT3 signaling pathway
doi: 10.3892/mmr.2016.4982
Figure Lengend Snippet: AG490 inhibits intimal proliferation, and p-JAK2 and p-STAT3 protein expression. After surgery (8 h), vascular tissue pathology of (A) experimental side (treated with AG490 and IL-1β) and (B) control side (treated with IL-1β only) tissue was examined by light microscopy and hematoxylin and eosin staining (magnification, ×200). (C) Statistical analysis of the intima/media ratio. (D) Protein expression levels of p-JAK2 and p-STAT3 in vascular tissue by western blot analysis. (E) Gray scale analysis of p-JAK2, and p-STAT3 protein expression levels. The results are expressed as the mean ± SD (n=5). # P<0.05 vs. the control side. IL, interleukin; p-, phosphorylated; JAK, janus kinase; STAT, signal transducer and activator of transcription; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.
Article Snippet: Co., Ltd., Nanjing, China),
Techniques: Expressing, Light Microscopy, Staining, Western Blot